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Peramivir efficacy is based on deparrment trials versus placebo in which the predominant influenza virus type was influenza A; in one trial, a very limited number logih subjects infected with influenza B virus were enrolled. There are no data available tn department of human services login use of peramivir for here of influenza. Baloxavir efficacy for initial FDA approval kf October was based on clinical trials in previously healthy outpatients 12 to 64 years old Hayden, Singledose baloxavir t reatment was superior to placebo and had similar clinical efficacy in time to alleviation of symptoms to a 5-day treatment course of oseltamivir.

Oral oseltamivir is preferred for treatment of pregnant people RasmussenPregnant people are recommended to receive the same antiviral dosing as non-pregnant people. Baloxavir is not recommended for the treatment of influenza in pregnant or breastfeeding llgin, as there are no available efficacy or safety data for baloxavir in this pregnant people Chow,and no available data on the presence of baloxavir in human milk, the effects on the breastfed infant, or the effects on milk production.

CDC does not recommend use of baloxavir for monotherapy of influenza in severely immunosuppressed persons. There are no available efficacy, safety, or resistance data for baloxavir monotherapy of influenza in severely immunosuppressed patients and emergence of resistance depart,ent treatment is a concern because of prolonged influenza viral replication in these patients.

When indicatedantiviral treatment should be started as soon as possible after illness onsetideally within tn department of human services login hours of symptom onset for the greatest clinical benefit.

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Where Does it Hurt.